What is Pregnyl?
The medicinal product contains a hormone called human chorionic gonadotropin (hCG), which is part of a group of medicinal products called gonadotropins. The effect of hCG on the body is the same as the luteinizing hormone (LH) released by the male and female pituitary glands. LH regulates the function of the genitals along with another pituitary hormone, the follicle-stimulating hormone (FSH) (ovaries in women and testes in men). For the normal growth and maturation of eggs and sperm, these hormones are important.
What is Pregnyl used for?
In females, It can lead to impaired fertility if the body itself does not produce enough FSH and LH. Regular injections of an FSH-containing hormonal medication will cause the egg to mature. The administration of this drug can affect subsequent egg release. It may also be used to stimulate ovulation in medical services for assisted reproduction. In males, It can be used alone or in conjunction with an FSH-containing drug in men with gonadal insufficiency, delayed puberty, or problems with sperm development. In certain cases, it may also be granted to boys who have not descended from either or both testicles.
Dosage of Pregnyl in females:
Induction of ovulation because of anovulation or follicular maturation disorder in infertility: Typically at the end of treatment 1 injection of 5,000-10,000 IU of a drug containing FSH. In controlled hyperstimulation systems, preparation of follicles for puncture: Typically at the end of treatment 1 injection of 5,000-10,000 IU of a drug containing FSH. Aid for luteal phases: During the 9 days following ovulation or after embryo transfer, 2-3 repeated injections of 1,000-3,000 IU can be given (for example on days 3, 6, and 9 after ovulation induction).
Dosage of Pregnyl in males: Hypogonadotropic hypogonadism: hypogonadism 1,000-2,000 IU 2-3 days a week, respectively. If infertility is the key condition, the medication can be given 2-3 times a week with another medicine containing follitropin (FSH). Before any progress in spermatogenesis can be expected, this procedure must last for at least 3 months. Replacement therapy with testosterone should be discontinued during this procedure. It is sometimes sufficient to sustain this enhancement by administering hCG alone when progress is achieved.
Pregnyl side effects:
Pregnyl can cause side effects, like all drugs, but not everybody gets them. Reactions at the injection site have been documented, such as bleeding, discomfort, redness, swelling and itching. Allergic reactions, mostly involving pain and rash at the injection site, have rarely been reported. Generalized reactions can occur in rare cases, such as rash and fever.